Human Health & Nutrition
Animal Nutrition
Innovation · Nature · Sustainability

Refine, Redefine leaf

Refine Biology, Redefining Nature

Powered by Plant Extraction and Synthetic Biology
A trusted innovation partner for the global health industry.

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About Refine

Natural. Effective. Sustainable.

Founded in 2007, Refine Biology strives to provide purer natural ingredients, high-efficiency solutions and eco-friendly innovation.

Driven by rigorous science and continuous exploration, we partner closely with customers to grasp their unique requirements. Breaking the boundaries of existing frameworks, we harness synthetic biology to create new opportunities for natural ingredients.

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80+ Countries GLOBAL PRESENCE
Global
2,400 m? R&D LABORATORY
Lab
60,000 MT ANNUAL FERMENTATION CAPACITY
Fermentation
Cert 3 Cert 2 Cert 5 Cert 6 Cert 4 Cert 7

Natural, Effective,
Sustainable Guardian

Industry Solutions

Driven by Innovation,
Tailored for You

Innovation-led, customer-focused. We supply premium natural ingredients and tailored solutions to accelerate your product development and business growth.

Natural Sweeteners

Natural Sweetener Platform

We provide erythritol, allulose, steviol glycosides, sweetness enhancers and customized sweetener blends for sugar-free and reduced-sugar food and beverage applications.

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Natural Sweetener Platform
Functional Ingredients

Functional Ingredients Platform

We develop functional ingredients for use in energy, weight management, healthy aging, beauty-from-within and general wellness formulations.

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Functional Ingredients Platform
Natural Flavor

Natural Flavor Platform

We carefully select premium botanicals, fruits and herbs to deliver authentic, well-balanced natural flavors and customized solutions for food and beverage applications.

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Natural Flavor Platform
Animal Health

Animal Nutrition

Focusing on natural alternatives to antibiotics and sustainable protein solutions, we support safer and more sustainable animal nutrition.

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Animal Nutrition
R&D to Mass Production

Full-Process Empowerment

Built upon six core technology platforms, we merge AI and synthetic biology to unlock innovation for natural product development.

We uphold every promise of nature to build global trust.

AI R&D Platform

AI-Driven Technology R&D Platform

Our integrated technology platforms boost product quality, process efficiency and supply reliability while lowering environmental footprint. We strive to drive sustainable development of natural ingredients and support the shift toward a low-carbon future.

  • Prokaryotic Microorganism Gene Editing Platform
  • Eukaryotic Microorganism Gene Editing Platform
  • High-Throughput Strain Screening & Directed Evolution Platform
  • Enzyme Engineering Platform
  • Fermentation Engineering Platform
  • Separation Engineering Platform
? 100+ Innovation Projects in Progress
Production Platform

From Biofoundry Innovation
to Industrial Production

Our three smart manufacturing sites in China bridge lab-scale biofoundry innovation and industrial production. Leveraging our proprietary Design-Build-Test-Learn workflow, we seamlessly translate engineered strain designs into commercial-scale fermentation.

News & Insights

Explore the latest updates, industry insights, and exhibition news from Refine.

Sugar Reduction vs. Sugar Replacement: How Should Manufacturers Approach Each
Sugar Reduction vs. Sugar Replacement: How Should Manufacturers Approach Each
Where the cut lands decides the route. Under 30% the sucrose stays in the recipe and the work is subtraction.…
Rare Sugars: Where Do They Fit in Food Formulation
Rare Sugars: Where Do They Fit in Food Formulation
Rare sugars fit where sucrose is doing physical work: frozen desserts, baked goods, yogurt, drinks and confectionery. In those products…
What Is Erythritol Made? From Fermentation to Food Ingredient
What Is Erythritol Made? From Fermentation to Food Ingredient
Erythritol is made from glucose. The glucose comes from corn, wheat or cassava starch, and one ton of starch breaks…
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Empowering Global Partners

Making every natural promise a solid foundation for earning global trust.

We uphold every promise of nature to build global trust.

Honoring Our Commitment to the Planet

Our integrated technology platforms boost product quality, process efficiency and supply reliability while lowering environment footprint. We strive to drive sustainable development of natural ingredients and support the shift toward a low-carbon future.

Supporting Carbon Neutrality

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